Search results for "Enrichment test"

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Residential greenness-related DNA methylation changes

2021

Abstract Background Residential greenness has been associated with health benefits, but its biological mechanism is largely unknown. Investigation of greenness-related DNA methylation profiles can contribute to mechanistic understanding of the health benefits of residential greenness. Objective To identify DNA methylation profiles associated with greenness in the immediate surroundings of the residence. Methods We analyzed genome-wide DNA methylation in 1938 blood samples (982 participants) from the Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults (SAPALDIA). We estimated residential greenness based on normalized difference vegetation index at 30 × 30 m cell (green3…

Pathway analysisAllergyPhysical activityStress copingHealth benefitsBiologySettore MED/01 - Statistica MedicaCohort StudiesEpigenomeAir PollutionEnvironmental healthEnrichment testHumansGE1-350EWASGeneral Environmental ScienceDNAMethylationGreenness DNA methylation EWAS Enrichment test Pathway analysis Allergy Physical activity Allostatic loadDNA MethylationAllostatic loadEnvironmental sciencesDifferentially methylated regionsGreennessDNA methylationSettore SECS-S/01 - StatisticaCohort study
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